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Transcriptional strand asymmetry Topography Assessment couldn't be done for transcriptional strand asymmetry as the quantity slot gacor maxwin of mutations fulfilling our constraints was insufficient or this signature wasn't still analysed.
The y-axis is definitely the reads counts from E.coli. The red/grey color with the bars denotes the presence/absence of clb genes given that the clb genes represent pks genomic island and encoding colibactin.
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In addition to The one base signature discussed to date, it is known that colibactin from pks+ E.coli also induces short deletions at T homopolymers9,thirteen. We investigated whether shorter T deletions at T homopolymers transpired in the two regular and most cancers crypts of our dataset. The quick T-del signature was even more obvious than the single foundation pks+ signature (SPS7/SBS88) and could be located in nearly all samples (Fig.
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